If you are coming from the Buenos Aires-La Plata highway, you can exit on 9 de Julio or Av. Ing. Huergo to Puerto Madero.
Option 9 de Julio:
Continue east heading to the river and the Obelisk, take highway A. Illia which ends on the intersection of Jerónimo Salguero and Costanera Norte Rafael Obligado. After the traffic light go into the Exhibition Hall through the entrance portic.
Opction Ing. Huergo:
Driving from the north, continue on to Av. Eduardo Madero. In Av. Córdoba there are two options.
Turn left and after some blocks turn right to Leandro N. Alem. Pass the train station Retiro which changes its name to Av. del Libertador and then Av. Figueroa Alcorta. Continue north to Jerónimo Salguero street (the first one after MALBA -Museum).